University of Guelph researchers are the first to uncover how the cannabis plant creates important pain-relieving molecules that are 30 times more powerful at reducing inflammation than Aspirin.

The discovery unlocks the potential to create a naturally derived pain treatment that would offer potent relief without the risk of addiction of other painkillers.

These molecules are non-psychoactive and they target the inflammation at the source, making them ideal painkillers.

Prof. Tariq Akhtar, Department of Molecular and Cellular Biology

Biosynthesis of cannflavins A and B from Cannabis sativa L.

Wyniki badania w skrócie:

  1. Cannflavin A and B are prenylated flavonoids that are unique to Cannabis sativa.
  2. Cannflavins exhibit anti-inflammatory activity that is thirty times that of aspirin.
  3. Cannflavins are synthesized via a branch point from the phenylpropanoid pathway.
  4. A single prenyltransferase converts chrysoeriol to cannflavin A and B.